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HSPA1A/HSPA1B Antibody

Product Specifications

Background

HSPA1A is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

NCBI Gene ID

33033304

Swiss Prot

P08107

Accession Number

P08107

Host

Rabbit

Reactivity

Human

Immunogen

This HSPA1A/HSPA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from human HSPA1A/HSPA1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Monkey, Rat, Chicken, Xenopus, Yeast, C. Elegans, Hamster, Zebrafish, Drosophila

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HSPA1A

NCBI Official Name

Heat shock 70 kDa protein 1A/1B

NCBI Organism

Homo sapiens

Background Reference 01

Mueller, T., et al., Transplantation 78 (2) :292-295 (2004) .

Background Reference 02

Fekete, A., et al., Pediatr. Res. 54 (4) :452-455 (2003) .

Background Reference 03

Broquet, A.H., et al., J. Biol. Chem. 278 (24) :21601-21606 (2003) .

Background Reference 04

Bruce, C.R., et al., Diabetes 52 (9) :2338-2345 (2003) .

Other Product Names

Heat shock 70 kDa protein 1A/1B, Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP701/HSP702, HSPA1A, HSPA1, HSX70

Tested Applications

WB

Protein ID

147744565

Physical Properties

Liquid

Frequently Asked Questions

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