Thrombopoietin Antibody
Product Specifications
Background
Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.
NCBI Gene ID
7066
Swiss Prot
P40225
Accession Number
P40225
Host
Rabbit
Reactivity
Human
Immunogen
This Thrombopoietin (TPO) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human Thrombopoietin (TPO) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-987
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
THPO
NCBI Official Name
Thrombopoietin
NCBI Organism
Homo sapiens
Background Reference 01
Baker, J.E., Cardiovasc. Res. 77 (1), 44-53 (2008)
Background Reference 02
Steinberg, O., J. Pediatr. Hematol. Oncol. 29 (12), 822-825 (2007)
Background Reference 03
Kanayasu-Toyoda, T., J. Biol. Chem. 282 (46), 33507-33514 (2007)
Other Product Names
Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF
Tested Applications
WB
Protein ID
730982
Physical Properties
Liquid
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