PBP Antibody
Product Specifications
Background
PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.
NCBI Gene ID
5473
Swiss Prot
P02775
Accession Number
P02775
Host
Rabbit
Reactivity
Human
Immunogen
This PBP (PPBP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-128 amino acids from the C-terminal region of human PBP (PPBP) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Symbol
PPBP
NCBI Official Name
Platelet basic protein
NCBI Organism
Homo sapiens
Background Reference 01
Majumdar S., J. Biol. Chem. 266:5785-5789 (1991)
Background Reference 02
Zhang C., Blood 98:610-617 (2001)
Background Reference 03
Aivado, M., Proc. Natl. Acad. Sci. U.S.A. 104 (4), 1307-1312 (2007)
Other Product Names
Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, TC-2, Connective tissue-activating peptide III (1-81), CTAP-III (1-81), Beta-thromboglobulin, Beta-TG, Neutrophil-activating peptide 2 (74), NAP-2 (74), Neutrophil-activating peptide 2 (73), NAP-2 (73), Neutrophil-activating peptide 2, NAP-2, TC-1, Neutrophil-activating peptide 2 (1-66), NAP-2 (1-66), Neutrophil-activating peptide 2 (1-63), NAP-2 (1-63), PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1
Tested Applications
WB, IHC-P
Protein ID
129874
Physical Properties
Liquid
Curated Selection
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