HIPK3 Antibody

Product Specifications

Background

HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.

NCBI Gene ID

10114

Swiss Prot

Q9H422

Accession Number

Q9H422

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This HIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1127-1156 amino acids from the C-terminal region of human HIPK3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

134 kDa

Fragment

Rabbit Ig

Symbol

HIPK3

NCBI Official Name

Homeodomain-interacting protein kinase 3

NCBI Organism

Homo sapiens

Background Reference 01

Blume-Jensen P, et al. Nature 2001. 411: 355.

Background Reference 02

Cantrell D, J. Cell Sci. 2001. 114: 1439.

Background Reference 03

JhiangOncogene 2000. 19: 5590.

Background Reference 04

Manning G, et al. Science 2002. 298: 1912.

Other Product Names

Homeodomain-interacting protein kinase 3, Androgen receptor-interacting nuclear protein kinase, ANPK, Fas-interacting serine/threonine-protein kinase, FIST, Homolog of protein kinase YAK1, HIPK3, DYRK6, FIST3, PKY