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HIPK2 Antibody

Product Specifications

Background

HIPK2, a member of the KIPK subfamily of Ser/Thr protein kinases, phosphorylates homeodomain transcription factors. It may play a role as a corepressor for homeodomain transcription factors. This nuclear protein has been shown to interact with TRADD. It is highly expressed in neuronal tissues, heart and kidney, and weakly expressed in a ubiquitous way. HIPK2 is a target for sumoylation, and when conjugated it is directed to nuclear speckles

NCBI Gene ID

28996

Swiss Prot

Q9H2X6

Accession Number

Q9H2X6

Host

Rabbit

Reactivity

Human

Immunogen

This HIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from human HIPK2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

131 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HIPK2

NCBI Official Name

Homeodomain-interacting protein kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Li, X., et al., Biochem. Biophys. Res. Commun. 277 (2) :513-517 (2000) .

Background Reference 02

Wang, Y., et al., Biochim. Biophys. Acta 1518 (1-2), 168-172 (2001) .

Other Product Names

Homeodomain-interacting protein kinase 2, hHIPk2, HIPK2

Tested Applications

WB

Protein ID

21431782

Physical Properties

Liquid

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