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DYRK1B Antibody

Product Specifications

Background

DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.

NCBI Gene ID

9149

Swiss Prot

Q9Y463

Accession Number

Q9Y463

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DYRK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-589 amino acids from the C-terminal region of human DYRK1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-970

Calculated Molecular Weight

69 kDa

Fragment

Rabbit Ig

Symbol

DYRK1B

NCBI Official Name

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

NCBI Organism

Homo sapiens

Background Reference 01

Lim, S., et al., J. Biol. Chem. 277 (51) :49438-49445 (2002) .

Background Reference 02

Lim, S., et al., J. Biol. Chem. 277 (28) :25040-25046 (2002) .

Background Reference 03

Lee, K., et al., Cancer Res. 60 (13) :3631-3637 (2000) .

Background Reference 04

Leder, S., et al., Biochem. Biophys. Res. Commun. 254 (2) :474-479 (1999) .

Other Product Names

Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinase, DYRK1B, MIRK

Tested Applications

WB, IHC-P

Protein ID

9296963

Physical Properties

Liquid

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