CLK1 Antibody
Product Specifications
Background
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection.
NCBI Gene ID
1195
Swiss Prot
P49759
Accession Number
P49759
Host
Rabbit
Reactivity
Human
Immunogen
This CLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human CLK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-968
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CLK1
NCBI Official Name
Dual specificity protein kinase CLK1
NCBI Organism
Homo sapiens
Background Reference 01
Prasad, J., et al., Mol. Cell. Biol. 23 (12) :4139-4149 (2003) . Talmadge, C.B., et al., Hum. Genet. 103 (4) :523-524 (1998) . Hanes, J., et al., J. Mol. Biol. 244 (5) :665-672 (1994) . Johnson, K.W., et al., J. Biol. Chem. 266 (6) :3402-3407 (1991) . Ben-David, Y., et al., EMBO J. 10 (2) :317-325 (1991) .
Other Product Names
Dual specificity protein kinase CLK1, CDC-like kinase 1, CLK1, CLK
Tested Applications
WB
Protein ID
206729857
Physical Properties
Liquid
Curated Selection
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