MAPK12 Antibody

Product Specifications

Background

P38 gamma is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. P38 gamma functions as a signal transducer during differentiation of myoblasts to myotubes.

NCBI Gene ID

6300

Swiss Prot

P53778

Accession Number

P53778

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MAPK12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-367 amino acids from the C-terminal region of human MAPK12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-961

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Symbol

MAPK12

NCBI Official Name

Mitogen-activated protein kinase 12

NCBI Organism

Homo sapiens

Background Reference 01

Garcia-Lora, A., et al., Cancer Immunol. Immunother. 52 (1) :59-64 (2003) .

Background Reference 02

Julien, C., et al., J. Biol. Chem. 278 (43) :42615-42624 (2003) .

Background Reference 03

Robinson, M.J., et al., J. Biol. Chem. 277 (7) :5094-5100 (2002) .

Background Reference 04

Court, N.W., et al., J. Mol. Cell. Cardiol. 34 (4) :413-426 (2002) .

Other Product Names

Mitogen-activated protein kinase 12, MAP kinase 12, MAPK 12, Extracellular signal-regulated kinase 6, ERK-6, Mitogen-activated protein kinase p38 gamma, MAP kinase p38 gamma, Stress-activated protein kinase 3, MAPK12, ERK6, SAPK3

Tested Applications

WB, IHC-P

Protein ID

2851522

Physical Properties

Liquid

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