MAPK13 Antibody

P38 delta is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.

This MAPK13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-365 amino acids from the C-terminal region of human MAPK13.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Duyndam, M.C., et al., J. Biol. Chem. 278 (9) :6885-6895 (2003) . Efimova, T., et al., J. Biol. Chem. 277 (35) :31753-31760 (2002) . Knebel, A., et al., EMBO J. 20 (16) :4360-4369 (2001) . Hu, M.C., et al., J. Biol. Chem. 274 (11) :7095-7102 (1999) . Parker, C.G., et al., Biochem. Biophys. Res. Commun. 249 (3) :791-796 (1998) .

Mitogen-activated protein kinase 13, MAP kinase 13, MAPK 13, Mitogen-activated protein kinase p38 delta, MAP kinase p38 delta, Stress-activated protein kinase 4, MAPK13, PRKM13, SAPK4