ERK3 Antibody
Product Specifications
Background
ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases) . MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
NCBI Gene ID
5597
Swiss Prot
Q16659
Accession Number
Q16659
Host
Rabbit
Reactivity
Human
Immunogen
This ERK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692~721 amino acids from the C-terminal region of human ERK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-953
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:500
Symbol
MAPK6
NCBI Official Name
Mitogen-activated protein kinase 6
NCBI Organism
Homo sapiens
Background Reference 01
Coulombe, P., et al., Mol. Cell. Biol. 23 (13) :4542-4558 (2003) .
Background Reference 02
Meloche, S., et al., Oncogene 13 (7) :1575-1579 (1996) .
Background Reference 03
Cheng, M., et al., J. Biol. Chem. 271 (15) :8951-8958 (1996) .
Background Reference 04
Zhu, A.X., et al., Mol. Cell. Biol. 14 (12) :8202-8211 (1994) .
Other Product Names
Mitogen-activated protein kinase 6, MAP kinase 6, MAPK 6, Extracellular signal-regulated kinase 3, ERK-3, MAP kinase isoform p97, p97-MAPK, MAPK6, ERK3, PRKM6
Tested Applications
ELISA, WB
Protein ID
2499596
Physical Properties
Liquid
Curated Selection
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