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NUP62 Antibody

Product Specifications

Background

NUP62 is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This protein is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. The protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals.

NCBI Gene ID

23636

Swiss Prot

P37198

Accession Number

P37198

Host

Rabbit

Reactivity

Human

Immunogen

This NUP62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human NUP62.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

NUP62

NCBI Official Name

Nuclear pore glycoprotein p62

NCBI Organism

Homo sapiens

Background Reference 01

Stochaj, U., Banski, P. Exp. Cell Res. 312 (13), 2490-2499 (2006)

Background Reference 02

Basel-Vanagaite, L., Muncher, L. Ann. Neurol. 60 (2), 214-222 (2006)

Background Reference 03

Guan, T., Muller, S. Mol. Biol. Cell (11), 1591-1603 (1995)

Other Product Names

Nuclear pore glycoprotein p62, 62 kDa nucleoporin, Nucleoporin Nup62, NUP62

Tested Applications

WB, IHC-P, Flow

Protein ID

134047855

Physical Properties

Liquid

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