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IGFALS Antibody

Product Specifications

Background

IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.

NCBI Gene ID

3483

Swiss Prot

P35858

Accession Number

P35858

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This IGFALS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the Central region of human IGFALS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Symbol

IGFALS

NCBI Official Name

Insulin-like growth factor-binding protein complex acid labile subunit

NCBI Organism

Homo sapiens

Background Reference 01

Leong S.R., Baxter R.C.Mol. Endocrinol. 6:870-876 (1992)

Background Reference 02

Suwanichkul A.Endocrinology 141:833-838 (2000)

Background Reference 03

Liu T., Qian W.-J.J. Proteome Res. 4:2070-2080 (2005)

Other Product Names

Insulin-like growth factor-binding protein complex acid labile subunit, ALS, IGFALS, ALS

Tested Applications

WB, IHC-P, Flow

Protein ID

543800

Physical Properties

Liquid

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