VTN Antibody

Product Specifications

Background

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

NCBI Gene ID

7448

Swiss Prot

P04004

Accession Number

P04004

Host

Rabbit

Reactivity

Human

Immunogen

This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the N-terminal region of human VTN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

VTN

NCBI Official Name

Vitronectin

NCBI Organism

Homo sapiens

Background Reference 01

Jenne D.E., Stanley K.K.EMBO J. 4:3153-3157 (1985) Sigurdardottir O., Wiman B.Biochim. Acta 1208:104-110 (1994) Seiffert D., Loskutoff D.J.J. Biol. Chem. 266:2824-2830 (1991)