EN2 Antibody
Product Specifications
Background
EN2 is thought to have a role in controlling development. In Drosophila, the protein plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. This protein has been implicated in the control of pattern formation during development of the central nervous system.
NCBI Gene ID
2020
Swiss Prot
P19622
Accession Number
P19622
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This EN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human EN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Symbol
EN2
NCBI Official Name
Homeobox protein engrailed-2
NCBI Organism
Homo sapiens
Background Reference 01
Poole S.J., Law M.L.Genomics 4:225-231 (1989)
Background Reference 02
Benayed R., Gharani N.Am. J. Hum. Genet. 77:851-868 (2005)
Other Product Names
Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2, EN2
Tested Applications
WB, IF
Protein ID
21903415
Physical Properties
Liquid
Curated Selection
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