SPRY4 Antibody
Product Specifications
Background
SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. The protein is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.
NCBI Gene ID
81848
Swiss Prot
Q9C004
Accession Number
Q9C004
Host
Rabbit
Reactivity
Human
Immunogen
This SPRY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-301 amino acids from the C-terminal region of human SPRY4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SPRY4
NCBI Official Name
Protein sprouty homolog 4
NCBI Organism
Homo sapiens
Background Reference 01
Tsai CF, et al. (2008) Proteome Res
Background Reference 02
Guo A, et al. (2008) Proc Natl Acad SciS105, 692-7
Background Reference 03
Rikova K, et al. (2007) Cell 131, 1190-203
Background Reference 04
Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM (2007) Proc Natl Acad SciS104, 5860-5
Other Product Names
Protein sprouty homolog 4, Spry-4, SPRY4
Tested Applications
WB
Protein ID
14916719
Physical Properties
Liquid
Curated Selection
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