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CAMK2A Antibody

Product Specifications

Background

CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.

NCBI Gene ID

815

Swiss Prot

Q9UQM7

Accession Number

Q9UQM7

Host

Rabbit

Reactivity

Human

Immunogen

This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human CAMK2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-898

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

CAMK2A

NCBI Official Name

Calcium/calmodulin-dependent protein kinase type II subunit alpha

NCBI Organism

Homo sapiens

Background Reference 01

Lee, C.W., Mol. Pharmacol. 73 (5), 1454-1464 (2008)

Background Reference 02

Yuan, K., Lab. Invest. 87 (9), 938-950 (2007)

Other Product Names

Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968

Tested Applications

WB, IHC-P

Protein ID

296434552

Physical Properties

Liquid

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