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MEN1 Antibody

Product Specifications

Background

Menin (MEN1), a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known.

NCBI Gene ID

4221

Swiss Prot

O00255

Accession Number

O00255

Host

Rabbit

Reactivity

Human

Immunogen

This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-144 amino acids from human MEN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Symbol

MEN1

NCBI Official Name

Menin

NCBI Organism

Homo sapiens

Background Reference 01

Hashimoto, M., Int. J. Oncol. 33 (2), 333-340 (2008)

Background Reference 02

Vidal, A., Eur Acad Dermatol Venereol 22 (7), 835-838 (2008)

Background Reference 03

Pieterman, C.R., Clin. Endocrinol. (Oxf) (2008)

Other Product Names

Menin, MEN1, SCG2

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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