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CSNK1A1 Antibody

Product Specifications

Background

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.

NCBI Gene ID

1452

Swiss Prot

P48729

Accession Number

P48729

Host

Rabbit

Reactivity

Human

Immunogen

This CSNK1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

CSNK1A1

NCBI Official Name

Casein kinase I isoform alpha

NCBI Organism

Homo sapiens

Background Reference 01

Liu, C., et al., Cell 108 (6) :837-847 (2002) .

Background Reference 02

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

Background Reference 03

Fish, K.J., et al., J. Biol. Chem. 270 (25) :14875-14883 (1995) .

Background Reference 04

Tapia, C., et al., FEBS Lett. 349 (2) :307-312 (1994) .

Other Product Names

Casein kinase I isoform alpha, CKI-alpha, CK1, CSNK1A1

Tested Applications

WB, IHC-P

Protein ID

31077177

Physical Properties

Liquid

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