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MYCN Antibody

Product Specifications

Background

MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.

NCBI Gene ID

4613

Swiss Prot

P04198

Accession Number

P04198

Host

Rabbit

Reactivity

Human

Immunogen

This MYCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human MYCN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-879

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MYCN

NCBI Official Name

N-myc proto-oncogene protein

NCBI Organism

Homo sapiens

Background Reference 01

Combaret, V., Pediatr Blood Cancer 53 (3), 329-331 (2009)

Background Reference 02

Alvarez-Rodriguez, R., J. Cell. Sci. 122 (PT 5), 595-599 (2009)

Background Reference 03

Jacobs, J.F., BMC Cancer 9, 239 (2009)

Other Product Names

N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37, MYCN, BHLHE37, NMYC

Tested Applications

WB

Protein ID

127604

Physical Properties

Liquid

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