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CYK18 Antibody

Product Specifications

Background

KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.

NCBI Gene ID

3875

Swiss Prot

P05783

Accession Number

P05783

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CYK18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human CYK18.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

KRT18

NCBI Official Name

Keratin, type I cytoskeletal 18

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, Q., Clin. Cancer Res. 15 (10), 3557-3567 (2009)

Background Reference 02

Kruse, R., Folia Histochem. Cytobiol. 47 (1), 127-130 (2009)

Background Reference 03

Toivola, D.M., Hepatology 40 (2), 459-466 (2004)

Other Product Names

Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

125083

Physical Properties

Liquid

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