FRIH Antibody
Product Specifications
Background
FRIH is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.
NCBI Gene ID
2495
Swiss Prot
P02794
Accession Number
P02794
Host
Rabbit
Reactivity
Human
Immunogen
This FRIH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-180 amino acids from the C-terminal region of human FRIH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FTH1
NCBI Official Name
Ferritin heavy chain
NCBI Organism
Homo sapiens
Background Reference 01
Coffman, L.G., Proc. Natl. Acad. Sci. U.S.A. 106 (2), 570-575 (2009)
Background Reference 02
Sammarco, M.C., J. Biol. Chem. 283 (8), 4578-4587 (2008)
Other Product Names
Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein, Ferritin heavy chain, N-terminally processed, FTH1, FTH, FTHL6
Tested Applications
WB
Protein ID
120516
Physical Properties
Liquid
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