NQO1 Antibody

NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) .

This NQO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-144 amino acids from the Central region of human NQO1.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Hubackova, M., Vaclavikova, R. Pharmacogenet. Genomics 19 (7), 505-512 (2009) Canova, C., Hashibe, M. Cancer Res. 69 (7), 2956-2965 (2009) Li, Y. and Jaiswal, A.K. J. Biol. Chem. 267 (21), 15097-15104 (1992)

NAD (P) H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD (P) H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1