Tyrosinase Antibody
Product Specifications
Background
TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation.
NCBI Gene ID
7299
Swiss Prot
P14679
Accession Number
P14679
Host
Rabbit
Reactivity
Human
Immunogen
This Tyrosinase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 486-513 amino acids from the C-terminal region of human Tyrosinase.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Symbol
TYR
NCBI Official Name
Tyrosinase
NCBI Organism
Homo sapiens
Background Reference 01
Ostankovitch, M. J. Immunol. 182 (8), 4830-4835 (2009)
Background Reference 02
Chintamaneni, C.D. Proc. Natl. Acad. Sci. U.S.A. 88 (12), 5272-5276 (1991)
Other Product Names
Tyrosinase, LB24-AB, Monophenol monooxygenase, SK29-AB, Tumor rejection antigen AB, TYR
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
401235
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
