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CP Antibody

Product Specifications

Background

CP is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II) transferrin to Fe (III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.

NCBI Gene ID

1356

Swiss Prot

P00450

Accession Number

P00450

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-577 amino acids from the Central region of human CP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

122 kDa

Fragment

Rabbit Ig

Symbol

CP

NCBI Official Name

Ceruloplasmin

NCBI Organism

Homo sapiens

Background Reference 01

Park, Y., Lee, I.S. Arch. Pharm. Res. 32 (5), 693-698 (2009)

Background Reference 02

Altamura, C., Squitti, R. Stroke 40 (4), 1282-1288 (2009)

Background Reference 03

Squitti, R., Quattrocchi, C.C. Prion (1), 23-27 (2008)

Other Product Names

Ceruloplasmin, Ferroxidase, CP

Tested Applications

WB, IHC-P, Flow

Protein ID

116117

Physical Properties

Liquid

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