CPN1 Antibody

Product Specifications

Background

CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.

NCBI Gene ID

1369

Swiss Prot

P15169

Accession Number

P15169

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human CPN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CPN1

NCBI Official Name

Carboxypeptidase N catalytic chain

NCBI Organism

Homo sapiens

Background Reference 01

Davis, D.A., Singer, K.E. Blood 105 (12), 4561-4568 (2005)

Background Reference 02

Riley, D.A., Tan, F. Genomics 50 (1), 105-108 (1998)

Background Reference 03

Hendriks, D., Vingron, M. Biol. Chem. Hoppe-Seyler 374 (9), 843-849 (1993)

Other Product Names

Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, Serum carboxypeptidase N, SCPN, CPN1, ACBP