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C1QA Antibody

Product Specifications

Background

C1QA is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on hromosome 1.

NCBI Gene ID

712

Swiss Prot

P02745

Accession Number

P02745

Host

Rabbit

Reactivity

Human

Immunogen

This C1QA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the C-terminal region of human C1QA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-823

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Symbol

C1QA

NCBI Official Name

Complement C1q subcomponent subunit A

NCBI Organism

Homo sapiens

Background Reference 01

Dardiotis, E., Koutsou, P. J. Neurol. Sci. (2009) In press

Background Reference 02

Martens, H.A., Zuurman, M.W. Ann. Rheum. Dis. 68 (5), 715-720 (2009)

Background Reference 03

Racila, E., Link, B.K. Clin. Cancer Res. 14 (20), 6697-6703 (2008)

Background Reference 04

Sjoberg, A.P., Nystrom, S. Mol. Immunol. 45 (11), 3213-3221 (2008)

Other Product Names

Complement C1q subcomponent subunit A, C1QA

Tested Applications

WB, IHC-P, Flow

Protein ID

399138

Physical Properties

Liquid

Curated Selection

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