C1QA Antibody
Product Specifications
Background
C1QA is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on hromosome 1.
NCBI Gene ID
712
Swiss Prot
P02745
Accession Number
P02745
Host
Rabbit
Reactivity
Human
Immunogen
This C1QA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the C-terminal region of human C1QA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Symbol
C1QA
NCBI Official Name
Complement C1q subcomponent subunit A
NCBI Organism
Homo sapiens
Background Reference 01
Dardiotis, E., Koutsou, P. J. Neurol. Sci. (2009) In press
Background Reference 02
Martens, H.A., Zuurman, M.W. Ann. Rheum. Dis. 68 (5), 715-720 (2009)
Background Reference 03
Racila, E., Link, B.K. Clin. Cancer Res. 14 (20), 6697-6703 (2008)
Background Reference 04
Sjoberg, A.P., Nystrom, S. Mol. Immunol. 45 (11), 3213-3221 (2008)
Other Product Names
Complement C1q subcomponent subunit A, C1QA
Tested Applications
WB, IHC-P, Flow
Protein ID
399138
Physical Properties
Liquid
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