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SERPINA3 Antibody

Product Specifications

Background

SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

NCBI Gene ID

12

Swiss Prot

P01011

Accession Number

P01011

Host

Rabbit

Reactivity

Human

Immunogen

This SERPINA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human SERPINA3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

SERPINA3

NCBI Official Name

Alpha-1-antichymotrypsin

NCBI Organism

Homo sapiens

Background Reference 01

Abraham, C.R., Shirahama, T. Neurobiol. Aging 11 (2), 123-129 (1990)

Background Reference 02

Baumann, U., Huber, R. J. Mol. Biol. 218 (3), 595-606 (1991)

Background Reference 03

Desrochers, P.E., Mookhtiar, K. J. Biol. Chem. 267 (7), 5005-5012 (1992)

Other Product Names

Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT

Tested Applications

WB, Flow

Protein ID

112874

Physical Properties

Liquid

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