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PLG Antibody

Product Specifications

Background

PLG is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase and tissue plasminogen activator. The main function of this protein is to dissolve fibrin clots. The protein, like trypsin, belongs to the family of serine proteinases.

NCBI Gene ID

5340

Swiss Prot

P00747

Accession Number

P00747

Host

Rabbit

Reactivity

Human

Immunogen

This PLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-175 amino acids from the N-terminal region of human PLG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-814

Calculated Molecular Weight

91 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PLG

NCBI Official Name

Plasminogen

NCBI Organism

Homo sapiens

Background Reference 01

Hofmann, S.C., Voith, U. J. Invest. Dermatol. 129 (7), 1730-1739 (2009)

Background Reference 02

Passero, C.J., Mueller, G.M. J. Biol. Chem. 283 (52), 36586-36591 (2008)

Background Reference 03

Ohyama, S., Harada, T. Eur. J. Biochem. 271 (4), 809-820 (2004)

Background Reference 04

Lee, H., Kim, H.K. Arch. Biochem. Biophys. 375 (2), 359-363 (2000)

Other Product Names

Plasminogen, Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B, PLG

Tested Applications

WB

Protein ID

130316

Physical Properties

Liquid

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