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Lefty Antibody

Product Specifications

Background

LEFTB is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products.

NCBI Gene ID

10637

Swiss Prot

O75610

Accession Number

O75610

Host

Rabbit

Reactivity

Human

Immunogen

This Lefty (LEFTB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-314 amino acids from the C-terminal region of human Lefty (LEFTB) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

LEFTY1

NCBI Official Name

Left-right determination factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Kosaki K., Am. J. Hum. Genet. 64:712-721 (1999)

Background Reference 02

Dvash, T., Stem Cells 25 (2), 465-472 (2007)

Background Reference 03

Besser, D., J. Biol. Chem. 279 (43), 45076-45084 (2004)

Other Product Names

Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B, LEFTY1, LEFTB, LEFTYB

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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