ADRB2 Antibody

Product Specifications

Background

ADRB2, beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein is intronless.

NCBI Gene ID

154

Swiss Prot

P07550

Accession Number

P07550

Host

Rabbit

Reactivity

Human

Immunogen

This ADRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from human ADRB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ADRB2

NCBI Official Name

Beta-2 adrenergic receptor

NCBI Organism

Homo sapiens

Background Reference 01

Kobilka B.K., Dixon R.A.F.Proc. Natl. Acad. Sci. U.S.A. 84:46-50 (1987)

Background Reference 02

Emorine L.J., Marullo S.Proc. Natl. Acad. Sci. U.S.A. 84:6995-6999 (1987)

Background Reference 03

Kobilka B.K., Frielle T.J. Biol. Chem. 262:7321-7327 (1987)

Other Product Names

Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR

Tested Applications

Protein ID

296439450

Physical Properties

Liquid

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