AMPK alpha Antibody
Product Specifications
Background
PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
NCBI Gene ID
5562
Swiss Prot
Q13131
Accession Number
Q13131
Host
Rabbit
Reactivity
Human
Immunogen
This AMPK alpha (PRKAA1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from human AMPK alpha (PRKAA1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction, Autophagy
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-772
Calculated Molecular Weight
64 kDa
Fragment
Rabbit Ig
Symbol
PRKAA1
NCBI Official Name
5'-AMP-activated protein kinase catalytic subunit alpha-1
NCBI Organism
Homo sapiens
Background Reference 01
Pang, T., J. Biol. Chem. 282 (1), 495-506 (2007)
Background Reference 02
Crawford, R.M., Cell. Signal. 18 (10), 1595-1603 (2006)
Background Reference 03
Crawford, R.M., Mol. Cell. Biol. 26 (15), 5921-5931 (2006)
Other Product Names
5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1
Tested Applications
WB, IHC-P
Protein ID
254763436
Physical Properties
Liquid
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