MAPK3 Antibody

Product Specifications

Background

MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.

NCBI Gene ID

5595

Swiss Prot

P27361

Accession Number

P27361

Host

Rabbit

Reactivity

Human

Immunogen

This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from human MAPK3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Drosophila, Bovine, Mouse, Rat, Xenopus, C. Elegans

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MAPK3

NCBI Official Name

Mitogen-activated protein kinase 3

NCBI Organism

Homo sapiens

Background Reference 01

Munshi, H.G., et al., J. Biol. Chem. 279 (37) :39042-39050 (2004) .

Background Reference 02

Mukherjee, S., et al., Infect. Immun. 72 (9) :5274-5282 (2004) .

Background Reference 03

Sebkova, L., et al., Infect. Immun. 72 (9) :5019-5026 (2004) .

Background Reference 04

Huang, H.M., et al., Biochem. Biophys. Res. Commun. 320 (4) :1247-1252 (2004) .

Other Product Names

Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, ERK1, PRKM3