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MARK3 Antibody

Product Specifications

Background

MARK proteins are involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2, and MAP4. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK3 may be involved in cell cycle regulation, and alterations in the MARK3 gene may lead to carcinogenesis.

NCBI Gene ID

4140

Swiss Prot

P27448

Accession Number

P27448

Host

Rabbit

Reactivity

Human

Immunogen

This MARK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-601 amino acids from the C-terminal region of human MARK3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-742

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

MARK3

NCBI Official Name

MAP/microtubule affinity-regulating kinase 3

NCBI Organism

Homo sapiens

Background Reference 01

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

Background Reference 02

Sun, T.Q., et al., Nat. Cell Biol. 3 (7) :628-636 (2001) .

Background Reference 03

Peng, C.Y., et al., Cell Growth Differ. 9 (3) :197-208 (1998) .

Other Product Names

MAP/microtubule affinity-regulating kinase 3, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, MARK3, CTAK1, EMK2

Tested Applications

WB, IHC-P

Protein ID

341941142

Physical Properties

Liquid

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