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SEPSH2 Antibody

Product Specifications

Background

This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop.

NCBI Gene ID

22928

Swiss Prot

Q99611

Accession Number

Q99611

Host

Rabbit

Reactivity

Human

Immunogen

This SEPSH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-201 amino acids from the Central region of human SEPSH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-714

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Symbol

SEPHS2

NCBI Official Name

Selenide, water dikinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Tamura, T., et al., Proc. Natl. Acad. Sci. U.S.A. 101 (46) :16162-16167 (2004) .

Background Reference 02

Lescure, A., et al., J. Biol. Chem. 274 (53) :38147-38154 (1999) .

Background Reference 03

Guimaraes, M.J., et al., Proc. Natl. Acad. Sci. U.S.A. 93 (26) :15086-15091 (1996) .

Background Reference 04

Guimaraes, M.J., et al., Development 121 (10) :3335-3346 (1995) .

Other Product Names

Selenide, water dikinase 2, Selenium donor protein 2, Selenophosphate synthase 2, SEPHS2, SPS2

Tested Applications

WB, IHC-P

Protein ID

172044671

Physical Properties

Liquid

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