PGK1 Antibody

Product Specifications

Background

Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. Phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and is proposed to participate in the angiogenic process as a disulfide reductase. Mutations in PGK1 may be associated with hemolytic anemia.

NCBI Gene ID

5230

Swiss Prot

P00558

Accession Number

P00558

Host

Rabbit

Reactivity

Human

Immunogen

This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human PGK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

PGK1

NCBI Official Name

Phosphoglycerate kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Shetty, S., et al., Am. J. Respir. Cell Mol. Biol. 31 (1) :100-106 (2004) .

Background Reference 02

Daly, E.B., et al., Biochim. Biophys. Acta 1691 (1) :17-22 (2004) .

Background Reference 03

Daly, E.B., et al., Int. J. Biol. Markers 19 (2) :170-172 (2004) .

Background Reference 04

Saito, Y., et al., Biochem. Biophys. Res. Commun. 314 (2) :396-402 (2004) .

Other Product Names

Phosphoglycerate kinase 1, Cell migration-inducing gene 10 protein, Primer recognition protein 2, PRP 2, PGK1, PGKA

Tested Applications

WB, IHC-P

Protein ID

52788229

Physical Properties

Liquid

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