PBK Antibody

Product Specifications

Background

PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

NCBI Gene ID

55872

Swiss Prot

Q96KB5

Accession Number

Q96KB5

Host

Rabbit

Reactivity

Human

Immunogen

This PBK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-317 amino acids from the C-terminal region of human PBK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

PBK

NCBI Official Name

Lymphokine-activated killer T-cell-originated protein kinase

NCBI Organism

Homo sapiens

Background Reference 01

Nandi, A., et al., Blood Cells Mol. Dis. 32 (1) :240-245 (2004) .

Background Reference 02

Simons-Evelyn, M., et al., Blood Cells Mol. Dis. 27 (5) :825-829 (2001) .

Background Reference 03

Zhao, S., et al., Int. J. Biochem. Cell Biol. 33 (6) :631-636 (2001) .

Background Reference 04

Abe, Y., et al., J. Biol. Chem. 275 (28) :21525-21531 (2000) .

Other Product Names

Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, CT84, MAPKK-like protein kinase, Nori-3, PDZ-binding kinase, Spermatogenesis-related protein kinase, SPK, T-LAK cell-originated protein kinase, PBK, TOPK