PANK1 Antibody

Product Specifications

Background

PANK1 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA.

NCBI Gene ID

53354

Swiss Prot

Q8TE04

Accession Number

Q8TE04

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the N-terminal region of human PANK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

64 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PANK1

NCBI Official Name

Pantothenate kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Ramaswamy, G., et al., J. Lipid Res. 45 (1) :17-31 (2004) .

Background Reference 02

Ni, X., et al., Int. J. Biochem. Cell Biol. 34 (2) :109-115 (2002) .

Background Reference 03

Zhou, B., et al., Nat. Genet. 28 (4) :345-349 (2001) .

Background Reference 04

Westaway, S.K., et al., Int. J. Biochem. Cell Biol. 34 (12), 1629 (2002) () : () .

Other Product Names

Pantothenate kinase 1, hPanK, hPanK1, Pantothenic acid kinase 1, PANK1, PANK

Tested Applications

Protein ID

27805665

Physical Properties

Liquid

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