NUAK2 Antibody
Product Specifications
Background
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
NCBI Gene ID
81788
Swiss Prot
Q9H093
Accession Number
Q9H093
Host
Rabbit
Reactivity
Human
Immunogen
This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NUAK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-691
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NUAK2
NCBI Official Name
NUAK family SNF1-like kinase 2
NCBI Organism
Homo sapiens
Background Reference 01
Lefebvre, D.L., et al., Biochem. J. 355 (Pt 2), 297-305 (2001) () : () .
Other Product Names
NUAK family SNF1-like kinase 2, Omphalocele kinase 2, SNF1/AMP kinase-related kinase, SNARK, NUAK2 {ECO:0000312|EMBL:AAH173061}, OMPHK2, SNARK
Tested Applications
WB
Protein ID
74761376
Physical Properties
Liquid
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