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NUAK2 Antibody

Product Specifications

Background

Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.

NCBI Gene ID

81788

Swiss Prot

Q9H093

Accession Number

Q9H093

Host

Rabbit

Reactivity

Human

Immunogen

This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NUAK2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NUAK2

NCBI Official Name

NUAK family SNF1-like kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Lefebvre, D.L., et al., Biochem. J. 355 (Pt 2), 297-305 (2001) () : () .

Other Product Names

NUAK family SNF1-like kinase 2, Omphalocele kinase 2, SNF1/AMP kinase-related kinase, SNARK, NUAK2 {ECO:0000312|EMBL:AAH173061}, OMPHK2, SNARK

Tested Applications

WB

Protein ID

74761376

Physical Properties

Liquid

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