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Guanylyl Cyclase alpha 1 Antibody

Product Specifications

Background

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

NCBI Gene ID

2982

Swiss Prot

Q02108

Accession Number

Q02108

Host

Rabbit

Reactivity

Human

Immunogen

This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

77 kDa

Fragment

Rabbit Ig

Symbol

GUCY1A3

NCBI Official Name

Guanylate cyclase soluble subunit alpha-3

NCBI Organism

Homo sapiens

Background Reference 01

Saino, M., et al., Oncol. Rep. 12 (1) :47-52 (2004) .

Background Reference 02

Zhou, Y., et al., Gene 245 (2) :319-328 (2000) .

Background Reference 03

Papapetropoulos, A., et al., J. Cell. Physiol. 167 (2) :213-221 (1996) .

Background Reference 04

Giuili, G., et al., Hum. Genet. 91 (3) :257-260 (1993) .

Other Product Names

Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3, GUC1A3, GUCSA3, GUCY1A1

Tested Applications

WB, IHC-P

Protein ID

7404351

Physical Properties

Liquid

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