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AMHR2 Antibody

Product Specifications

Background

The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.

NCBI Gene ID

269

Swiss Prot

Q16671

Accession Number

Q16671

Host

Rabbit

Reactivity

Human

Immunogen

This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human AMHR2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-667

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AMHR2

NCBI Official Name

Anti-Muellerian hormone type-2 receptor

NCBI Organism

Homo sapiens

Background Reference 01

Picard, J.Y., et al., J. Soc. Biol. 196 (3) :217-221 (2002) .

Background Reference 02

Teixeira, J., et al., Endocr. Rev. 22 (5) :657-674 (2001) .

Background Reference 03

Imbeaud, S., et al., Nat. Genet. 11 (4) :382-388 (1995) .

Background Reference 04

Visser, J.A., et al., Biochem. Biophys. Res. Commun. 215 (3) :1029-1036 (1995) .

Other Product Names

Anti-Muellerian hormone type-2 receptor, Anti-Muellerian hormone type II receptor, AMH type II receptor, MIS type II receptor, MISRII, MRII, AMHR2, AMHR, MISR2

Tested Applications

WB

Protein ID

9087133

Physical Properties

Liquid

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