NEK8 Antibody
Product Specifications
Background
NEK8 is a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.
NCBI Gene ID
284086
Swiss Prot
Q86SG6
Accession Number
Q86SG6
Host
Rabbit
Reactivity
Human
Immunogen
This NEK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-604 amino acids from the C-terminal region of human NEK8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NEK8
NCBI Official Name
Serine/threonine-protein kinase Nek8
NCBI Organism
Homo sapiens
Background Reference 01
Valkova, N. et al. Mol. Cell Proteomics (7), 1009-1018 (2005)
Background Reference 02
Bowers, A.J. et al. Gene 328, 135-142 (2004)
Background Reference 03
Holland, P.M. et al. J. Biol. Chem. 277 (18), 16229-16240 (2002)
Other Product Names
Serine/threonine-protein kinase Nek8, Never in mitosis A-related kinase 8, NimA-related protein kinase 8, Nima-related protein kinase 12a, NEK8, JCK, NEK12A
Tested Applications
WB
Protein ID
34098463
Physical Properties
Liquid
Frequently Asked Questions
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