NEK8 Antibody

Product Specifications

Background

NEK8 is a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.

NCBI Gene ID

284086

Swiss Prot

Q86SG6

Accession Number

Q86SG6

Host

Rabbit

Reactivity

Human

Immunogen

This NEK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-604 amino acids from the C-terminal region of human NEK8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

75 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NEK8

NCBI Official Name

Serine/threonine-protein kinase Nek8

NCBI Organism

Homo sapiens

Background Reference 01

Valkova, N. et al. Mol. Cell Proteomics (7), 1009-1018 (2005)

Background Reference 02

Bowers, A.J. et al. Gene 328, 135-142 (2004)

Background Reference 03

Holland, P.M. et al. J. Biol. Chem. 277 (18), 16229-16240 (2002)

Other Product Names

Serine/threonine-protein kinase Nek8, Never in mitosis A-related kinase 8, NimA-related protein kinase 8, Nima-related protein kinase 12a, NEK8, JCK, NEK12A