DCK Antibody
Product Specifications
Background
Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
NCBI Gene ID
1633
Swiss Prot
P27707
Accession Number
P27707
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This DCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human DCK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-650
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
DCK
NCBI Official Name
Deoxycytidine kinase
NCBI Organism
Homo sapiens
Background Reference 01
Chottiner, E. G., et al. Proc. Nat. Acad. Sci. 88: 1531-1535 (1991) .
Other Product Names
Deoxycytidine kinase, dCK, DCK
Tested Applications
WB, IHC-P, IF, IP
Protein ID
118447
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
