Enniatin B1
Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM in an enzyme assay using rat liver microsomes[1]. Enniatin B1 crosss the blood-brain barrier[2]. Enniatin B1 decreases the activation of ERK (p44/p42) . Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation[3].
Product Specifications
CAS Number
19914-20-6
UNSPSC
12352005
Hazard Statement
H301+H311+H331
Target
Acyltransferase; ERK; NF-κB
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/enniatin-b1.html
Purity
99.34
Solubility
DMSO : ≥ 10 mg/mL
Smiles
CC[C@@H]([C@]1([H])N(C([C@H](OC([C@](N(C([C@@H](C(C)C)OC([C@H](C(C)C)N(C)C([C@](C(C)C)([H])OC1=O)=O)=O)=O)C)([H])C(C)C)=O)C(C)C)=O)C)C
Molecular Formula
C34H59N3O9
Molecular Weight
653.85
Precautions
H301+H311+H331
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ACAT; ERK; NF-κB
Available Sizes
Frequently Asked Questions
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