WNK3 Antibody
Product Specifications
Background
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]) .[supplied by OMIM]
NCBI Gene ID
65267
Swiss Prot
Q9BYP7
Accession Number
Q9BYP7
Host
Rabbit
Reactivity
Human
Immunogen
This WNK3 (PRKWNK3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1586-1616 amino acids from the C-terminal region of human WNK3 (PRKWNK3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
198 kDa
Fragment
Rabbit Ig
Symbol
WNK3
NCBI Official Name
Serine/threonine-protein kinase WNK3
NCBI Organism
Homo sapiens
Background Reference 01
Verissimo, F., et al., Oncogene 20 (39) :5562-5569 (2001) .
Background Reference 02
Nagase, T., et al., DNA Res. 7 (4) :273-281 (2000) .
Other Product Names
Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase with no lysine 3, WNK3, KIAA1566, PRKWNK3
Tested Applications
WB, IHC-P
Protein ID
353526307
Physical Properties
Liquid
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