PDK4 Antibody
Product Specifications
Background
PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
NCBI Gene ID
5166
Swiss Prot
Q16654
Accession Number
Q16654
Host
Rabbit
Reactivity
Human
Immunogen
This PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-277 amino acids from human PDK4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
PDK4
NCBI Official Name
[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Rosa, G., et al., Obes. Res. 11 (2) :176-182 (2003) . Razeghi, P., et al., Cardiology 97 (4) :203-209 (2002) . Rowles, J., et al., J. Biol. Chem. 271 (37) :22376-22382 (1996) . Gudi, R., et al., J. Biol. Chem. 270 (48) :28989-28994 (1995) .
Other Product Names
[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4
Tested Applications
WB, IHC-P
Protein ID
3183120
Physical Properties
Liquid
Frequently Asked Questions
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