PDK4 Antibody

Product Specifications

Background

PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

NCBI Gene ID

5166

Swiss Prot

Q16654

Accession Number

Q16654

Host

Rabbit

Reactivity

Human

Immunogen

This PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-277 amino acids from human PDK4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Symbol

PDK4

NCBI Official Name

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Rosa, G., et al., Obes. Res. 11 (2) :176-182 (2003) . Razeghi, P., et al., Cardiology 97 (4) :203-209 (2002) . Rowles, J., et al., J. Biol. Chem. 271 (37) :22376-22382 (1996) . Gudi, R., et al., J. Biol. Chem. 270 (48) :28989-28994 (1995) .