PKC eta Antibody
Product Specifications
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC eta is one of the PKC family members. This protein is most abundant in lung, less in heart and skin.
NCBI Gene ID
5583
Swiss Prot
P24723
Accession Number
P24723
Host
Rabbit
Reactivity
Human
Immunogen
This PKC eta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the N-terminal region of human PKC eta.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
78 kDa
Fragment
Rabbit Ig
Symbol
PRKCH
NCBI Official Name
Protein kinase C eta type
NCBI Organism
Homo sapiens
Background Reference 01
Palmer, R.H., et al., FEBS Lett. 356 (1) :5-8 (1994) .
Background Reference 02
Bacher, N., et al., Mol. Cell. Biol. 11 (1) :126-133 (1991) .
Background Reference 03
Bacher, N., et al., Mol. Cell. Biol. 12 (3), 1404 (1992) .
Other Product Names
Protein kinase C eta type, PKC-L, nPKC-eta, PRKCH, PKCL, PRKCL
Tested Applications
WB, IHC-P
Protein ID
281185512
Physical Properties
Liquid
Curated Selection
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