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PKC delta Antibody

Product Specifications

Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC delta is one of the PKC family members, and may play a role in antigen-dependent control of B-cell function.

NCBI Gene ID

5580

Swiss Prot

Q05655

Accession Number

Q05655

Host

Rabbit

Reactivity

Human

Immunogen

This PKC delta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the N-terminal region of human PKC delta.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Symbol

PRKCD

NCBI Official Name

Protein kinase C delta type

NCBI Organism

Homo sapiens

Background Reference 01

Nomoto, S., et al., Genes Cells 2 (10) :601-614 (1997) .

Background Reference 02

Aris, J.P., et al., Biochim. Biophys. Acta 1174 (2) :171-181 (1993) .

Other Product Names

Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Protein kinase C delta type regulatory subunit, Protein kinase C delta type catalytic subunit, Sphingosine-dependent protein kinase-1, SDK1, PRKCD

Tested Applications

WB, IHC-P

Protein ID

205371776

Physical Properties

Liquid

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